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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62340
Species: Mus musculus
RGD Object: Gene
Symbol: Top2a
Name: topoisomerase (DNA) II alpha
Acc ID: CHEBI:88297
Term: 9-hydroxyellipticine
Definition: A organic heterotetracyclic compound that is ellipticine in which the hydrogen at position 9 has been replaced by a hydroxy group.
Chemical ID: MESH:C008009
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Top2aaffects response to substanceISOTOP2A (Homo sapiens)6480464CTDTOP2A protein affects the susceptibility to 9-hydroxyellipticinePMID:23293027
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