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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619951
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb1a
Name: ATP binding cassette subfamily B member 1A
Acc ID: CHEBI:8828
Term: rhodamine 123
Definition: A xanthene dye that has formula C21H17ClN2O3.
Chemical ID: MESH:D020112
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb1aincreases exportISORGD:7308236480464CTDABCB1 protein results in increased export of Rhodamine 123

PMID:25058526 PMID:27816545 PMID:30391378
Abcb1amultiple interactionsISORGD:7308236480464CTD5-oxo-hexahydroquinoline analog inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123] abemaciclib inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123] CEP 33779 inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123] Verapamil inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]

PMID:25058526 PMID:27816545 PMID:30391378
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