Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	730846
Species:	Homo sapiens
RGD Object:	Gene
Symbol:	CASP8
Name:	caspase 8

Acc ID:	CHEBI:8825
Term:	Rhein
Definition:	A dihydroxyanthraquinone that has formula C15H8O6.
Chemical ID:	MESH:C020491

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
CASP8	increases cleavage	EXP		6480464	CTD	rhein results in increased cleavage of CASP8 protein	PMID:31436023

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.