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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10198
Species: Mus musculus
RGD Object: Gene
Symbol: Atf3
Name: activating transcription factor 3
Acc ID: CHEBI:8776
Term: ranitidine
Definition: A member of the class of furans used to treat peptic ulcer disease (PUD) and gastroesophageal reflux disease.
Chemical ID: MESH:D011899
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atf3multiple interactionsISOAtf3 (Rattus norvegicus)6480464CTD[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ATF3 mRNA; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of ATF3 mRNA]PMID:16401727 PMID:16415329
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