Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	3171
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Nfkbia
Name:	NFKB inhibitor alpha

Acc ID:	CHEBI:87697
Term:	prasugrel hydrochloride
Definition:	A racemate comprising equal amounts of (R)- and (S)-prasugrel hydrochloride. Used to prevent blood clots in people with acute coronary syndrome who are undergoing a procedure after a recent heart attack or stroke, and in people with certain disorders of the heart or blood vessels.
Chemical ID:	MESH:D000068799

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Nfkbia	multiple interactions	EXP		6480464	CTD	Prasugrel Hydrochloride inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased sumoylation of NFKBIA protein]	PMID:34174262

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