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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736021
Species: Homo sapiens
RGD Object: Gene
Symbol: APP
Name: amyloid beta precursor protein
Acc ID: CHEBI:87639
Term: azure B
Definition: An organic chloride salt having 3-(dimethylamino)-7-(methylamino)phenothiazin-5-ium as the counterion. It is used in making azure eosin stains for blood smear staining and is an active metabolite of methylene blue.
Chemical ID: MESH:C025819
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
APPmultiple interactionsEXP 6480464CTD[Azure B affects the cleavage of APP protein] which results in decreased secretion of APP protein modified form, Azure B results in decreased expression of and affects the cleavage of APP protein

PMID:30500345
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