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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1606566
Species: Homo sapiens
RGD Object: Gene
Symbol: BACE1
Name: beta-secretase 1
Acc ID: CHEBI:87639
Term: azure B
Definition: An organic chloride salt having 3-(dimethylamino)-7-(methylamino)phenothiazin-5-ium as the counterion. It is used in making azure eosin stains for blood smear staining and is an active metabolite of methylene blue.
Chemical ID: MESH:C025819
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BACE1decreases activityEXP 6480464CTDAzure B results in decreased activity of BACE1 protein

PMID:30500345
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.