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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1353911
Species: Homo sapiens
RGD Object: Gene
Symbol: OGG1
Name: 8-oxoguanine DNA glycosylase
Acc ID: CHEBI:87397
Term: aurintricarboxylic acid
Definition: A member of the class of quinomethanes that is 3-methylidene-6-oxocyclohexa-1,4-diene-1-carboxylic acid in which the methylidene hydrogens are replaced by 4-carboxy-3-hydroxyphenyl groups. The trisodium salt is the biological stain 'chrome violet CG' while the triammonium salt is 'aluminon'.
Chemical ID: MESH:D001312
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
OGG1decreases activityEXP 6480464CTDAurintricarboxylic Acid results in decreased activity of OGG1 proteinPMID:26218629
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