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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68384
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccnd1
Name: cyclin D1
Acc ID: CHEBI:8711
Term: quinacrine
Definition: A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Chemical ID: MESH:D011796
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:685566480464CTDQuinacrine results in decreased expression of CCND1 protein

PMID:28720477
multiple interactionsISORGD:685566480464CTDGSK3B protein affects the reaction [Quinacrine results in decreased expression of CCND1 protein]

PMID:28720477
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.