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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1592221
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mlkl
Name: mixed lineage kinase domain like pseudokinase
Acc ID: CHEBI:8708
Term: quetiapine fumarate
Definition: A fumarate salt that has formula (C21H25N3O2S)2.C4H4O4.
Chemical ID: MESH:D000069348
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mlklmultiple interactionsISORGD:15508186480464CTD1 1-dimethylbutyl-1-deoxy-Delta9-THC inhibits the reaction [Quetiapine Fumarate affects the localization of MLKL protein] 1 1-dimethylbutyl-1-deoxy-Delta9-THC inhibits the reaction [Quetiapine Fumarate results in increased expression of and results in increased phosphorylation of MLKL protein] AM 1241 inhibits the reaction [Quetiapine Fumarate affects the localization of MLKL protein] AM 1241 inhibits the reaction [Quetiapine Fumarate results in increased expression of and results in increased phosphorylation of MLKL protein] AM 281 inhibits the reaction [Quetiapine Fumarate affects the localization of MLKL protein] AM 281 inhibits the reaction [Quetiapine Fumarate results in increased phosphorylation of MLKL protein] Quetiapine Fumarate results in increased expression of and affects the localization of MLKL protein Quetiapine Fumarate results in increased expression of and results in increased phosphorylation of MLKL protein Rimonabant inhibits the reaction [Quetiapine Fumarate affects the localization of MLKL protein] Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of and results in increased phosphorylation of MLKL protein]

PMID:31220554
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