GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | STAT3 | multiple interactions | EXP | | 127284846 | RGD | Stattic inhibits the reaction [Il-6 increases phosphorylation of STAT3 protein in the stomach) | | STAT3 | decreases phosphorylation | EXP | | 6480464 | CTD | stattic results in decreased phosphorylation of STAT3 protein | PMID:24627483 | STAT3 | multiple interactions | EXP | | 6480464 | CTD | stattic affects the reaction [Arsenicals affects the phosphorylation of STAT3 protein]; stattic affects the reaction [IL6 protein affects the phosphorylation of STAT3 protein]; stattic inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] | PMID:23255093 PMID:24627483 PMID:25740948 PMID:29341321 | STAT3 | multiple interactions | ISO | Stat3 (Rattus norvegicus) | 6480464 | CTD | stattic inhibits the reaction [zoniporide results in increased phosphorylation of STAT3 protein] | PMID:20942815 | STAT3 | multiple interactions | ISO | Stat3 (Mus musculus) | 6480464 | CTD | stattic inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [deoxynivalenol results in increased expression of STAT3 mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [T-2 Toxin results in increased expression of STAT3 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein] | PMID:22454431 PMID:25740948 PMID:28739487 | |
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