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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1606566
Species: Homo sapiens
RGD Object: Gene
Symbol: BACE1
Name: beta-secretase 1
Acc ID: CHEBI:8674
Term: pyrimethanil
Definition: A member of the class of aminopyrimidines that is N-phenylpyrimidin-2-amine carrying two additional methyl substituents at positions 4 and 6. A fungicide used to control grey mould on fruit, vegetables and ornamentals as well as leaf scab on pome fruit. Also commonly employed to control Botrytis cinerea throughout the winemaking process in grapes, must, fermenting must and wine.
Chemical ID: MESH:C108337
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BACE1multiple interactionsISOBace1 (Mus musculus)6480464CTD[cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] results in increased expression of BACE1 proteinPMID:31939705
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