GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ache | decreases activity | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | Pyridostigmine Bromide results in decreased activity of ACHE protein | PMID:11248143 PMID:30176331 PMID:30682440 | Ache | decreases activity | ISO | ACHE (Homo sapiens) | 6480464 | CTD | Pyridostigmine Bromide results in decreased activity of ACHE protein | PMID:21354413 PMID:21414391 | Ache | decreases expression | ISO | ACHE (Homo sapiens) | 6480464 | CTD | Pyridostigmine Bromide results in decreased expression of ACHE protein | PMID:31175926 | Ache | multiple interactions | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | [Pyridostigmine Bromide co-treated with DEET] results in decreased activity of ACHE protein; [Pyridostigmine Bromide co-treated with DEET] results in increased activity of ACHE protein; [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] results in decreased activity of ACHE protein; [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] results in increased activity of ACHE protein; [Pyridostigmine Bromide co-treated with Permethrin] results in decreased activity of ACHE protein; [Pyridostigmine Bromide co-treated with Permethrin] results in increased activity of ACHE protein; asoxime chloride affects the reaction [Pyridostigmine Bromide results in decreased activity of ACHE protein]; asoxime chloride promotes the reaction [Pyridostigmine Bromide inhibits the reaction [Soman results in decreased activity of ACHE protein]]; Pyridostigmine Bromide inhibits the reaction [Soman results in decreased activity of ACHE protein] | PMID:11248143 PMID:14751452 PMID:30176331 PMID:30682440 | Ache | multiple interactions | ISO | ACHE (Homo sapiens) | 6480464 | CTD | Pyridostigmine Bromide inhibits the reaction [Soman results in decreased activity of ACHE protein]; SOD2 protein SNP promotes the reaction [Pyridostigmine Bromide results in decreased expression of ACHE protein] | PMID:21414391 PMID:31175926 | | ||||||||||||||||||||||
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