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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69213
Species: Homo sapiens
RGD Object: Gene
Symbol: ESR2
Name: estrogen receptor 2
Acc ID: CHEBI:8633
Term: puerarin
Definition: A hydroxyisoflavone that is isoflavone substituted by hydroxy groups at positions 7 and 4' and a beta-D-glucopyranosyl residue at position 8 via a C-glycosidic linkage.
Chemical ID: MESH:C033607
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ESR2decreases activityEXP 6480464CTDpuerarin results in decreased activity of ESR2 proteinPMID:18937077
ESR2decreases expressionEXP 6480464CTDpuerarin results in decreased expression of ESR2 mRNAPMID:20706672
ESR2decreases expressionISOEsr2 (Rattus norvegicus)6480464CTDpuerarin results in decreased expression of ESR2 mRNAPMID:22919047
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