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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621195
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgr1
Name: prostaglandin reductase 1
Acc ID: CHEBI:86228
Term: dithionitrobenzoic acid
Definition: An organic disulfide that results from the formal oxidative dimerisation of 2-nitro-5-thiobenzoic acid. An indicator used to quantify the number or concentration of thiol groups.
Chemical ID: MESH:D004228
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgr1multiple interactionsEXP 6480464CTDDithionitrobenzoic Acid inhibits the reaction [PTGR1 protein results in increased reduction of 10-nitro-oleic acid analog] Dithionitrobenzoic Acid inhibits the reaction [PTGR1 protein results in increased reduction of 15-ketoprostaglandin E2]

PMID:23878198
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