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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2048
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adora1
Name: adenosine A1 receptor
Acc ID: CHEBI:86228
Term: dithionitrobenzoic acid
Definition: An organic disulfide that results from the formal oxidative dimerisation of 2-nitro-5-thiobenzoic acid. An indicator used to quantify the number or concentration of thiol groups.
Chemical ID: MESH:D004228
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adora1multiple interactionsEXP 6480464CTD[Dithiothreitol co-treated with Dithionitrobenzoic Acid] inhibits the reaction [2-chloro-N6cyclopentyladenosine binds to ADORA1 protein] Cadmium Chloride promotes the reaction [Dithionitrobenzoic Acid inhibits the reaction [2-chloro-N6cyclopentyladenosine binds to ADORA1 protein]] Dithionitrobenzoic Acid inhibits the reaction [2-chloro-N6cyclopentyladenosine binds to ADORA1 protein] Dithionitrobenzoic Acid promotes the reaction [Cadmium Chloride inhibits the reaction [2-chloro-N6cyclopentyladenosine binds to ADORA1 protein]] Dithiothreitol inhibits the reaction [Dithionitrobenzoic Acid inhibits the reaction [2-chloro-N6cyclopentyladenosine binds to ADORA1 protein]]

PMID:10413299
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