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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352960
Species: Homo sapiens
RGD Object: Gene
Symbol: CES1
Name: carboxylesterase 1
Acc ID: CHEBI:85867
Term: p-nitrophenyl butyrate
Definition: A butyrate ester resulting from the formal condensation of the hydroxy group of 4-nitrophenol with the carboxy group of butyric acid.
Chemical ID: MESH:C033592
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CES1increases hydrolysisEXP 6480464CTDCES1 protein results in increased hydrolysis of 4-nitrophenyl butyratePMID:11950785
CES1multiple interactionsEXP 6480464CTDCES1 protein binds to and results in increased hydrolysis of 4-nitrophenyl butyratePMID:16282638
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