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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2180
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atp7b
Name: ATPase copper transporting beta
Acc ID: CHEBI:85609
Term: satraplatin
Definition: A platinum coordination entity that consists of a central platunum atom bound to chloro (x2), acetate (x2), amino, and cyclohexylamino groups. Used for treatment of advanced prostate cancer.
Chemical ID: MESH:C081294
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atp7bdecreases response to substanceISORGD:102176480464CTDATP7B protein results in decreased susceptibility to satraplatin metabolite

PMID:16170571
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