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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619717
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tuba1a
Name: tubulin, alpha 1A
Acc ID: CHEBI:85164
Term: nintedanib
Definition: A member of the class of oxindoles that is a kinase inhibitor used (in the form of its ethylsulfonate salt) for the treatment of idiopathic pulmonary fibrosis and cancer.
Chemical ID: MESH:C530716
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tuba1adecreases expressionISOTuba1a (Mus musculus)6480464CTDnintedanib results in decreased expression of TUBA1A mRNAPMID:27015953
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