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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621663
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Csnk2a1
Name: casein kinase 2 alpha 1
Acc ID: CHEBI:85085
Term: KT 5720
Definition: An organic heterooctacyclic compound that is 1H,1'H-2,2'-biindole in which the nitrogens have undergone formal oxidative coupling to positions 2 and 5 of hexyl (3S)-3-hydroxy-2-methyltetrahydrofuran-3-carboxylate (the 2R,3S,5S product), and in which the 3 and 3' positions of the biindole moiety have also undergone formal oxidative coupling to positions 3 and 4 of 1,5-dihydro-2H-pyrrol-2-one.
Chemical ID: MESH:C057416
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7333246480464CTDKT 5720 inhibits the reaction [cilostazol results in increased phosphorylation of CSNK2A1 protein]

PMID:24254769
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.