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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621288
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ncr1
Name: natural cytotoxicity triggering receptor 1
Acc ID: CHEBI:85083
Term: sofosbuvir
Definition: A nucleotide conjugate that is used in combination with ledipasvir (under the trade name Harvoni) for the treatment of chronic hepatitis C genotype 1 infection.
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ncr1affects expression ISONCR1 (Homo sapiens)40400920RGDsofosbuvir co-treated with ledipasvir affects expression of NCR1 protein in natural killer cells 
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