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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734433
Species: Homo sapiens
RGD Object: Gene
Symbol: ABCC6
Name: ATP binding cassette subfamily C member 6
Acc ID: CHEBI:8502
Term: 6-propyl-2-thiouracil
Definition: A pyrimidinethione consisting of uracil in which the 2-oxo group is substituted by a thio group and the hydrogen at position 6 is substituted by a propyl group.
Chemical ID: MESH:D011441
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ABCC6affects expressionISOAbcc6 (Rattus norvegicus)6480464CTDPropylthiouracil affects the expression of ABCC6 mRNAPMID:19483382
ABCC6increases expressionISOAbcc6 (Rattus norvegicus)6480464CTDPropylthiouracil results in increased expression of ABCC6 mRNAPMID:24780913
ABCC6multiple interactionsISOAbcc6 (Mus musculus)6480464CTD[Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of ABCC6 mRNAPMID:36706583
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