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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731911
Species: Mus musculus
RGD Object: Gene
Symbol: Mmp9
Name: matrix metallopeptidase 9
Acc ID: CHEBI:8502
Term: 6-propyl-2-thiouracil
Definition: A pyrimidinethione consisting of uracil in which the 2-oxo group is substituted by a thio group and the hydrogen at position 6 is substituted by a propyl group.
Chemical ID: MESH:D011441
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp9decreases expressionISOMmp9 (Rattus norvegicus)6480464CTDPropylthiouracil results in decreased expression of MMP9 mRNAPMID:24534949 PMID:24780913
Mmp9multiple interactionsISOMmp9 (Rattus norvegicus)6480464CTDPropylthiouracil inhibits the reaction [Aminopropionitrile results in increased expression of MMP9 protein]PMID:33462684
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