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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2087
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aldh1a1
Name: aldehyde dehydrogenase 1 family, member A1
Acc ID: CHEBI:8502
Term: 6-propyl-2-thiouracil
Definition: A pyrimidinethione consisting of uracil in which the 2-oxo group is substituted by a thio group and the hydrogen at position 6 is substituted by a propyl group.
Chemical ID: MESH:D011441
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh1a1affects expressionEXP 6480464CTDPropylthiouracil affects the expression of ALDH1A1 mRNAPMID:19483382
Aldh1a1decreases expressionEXP 6480464CTDPropylthiouracil results in decreased expression of ALDH1A1 mRNAPMID:24780913 PMID:25825206
Aldh1a1multiple interactionsISOAldh1a1 (Mus musculus)6480464CTD[Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of ALDH1A1 mRNAPMID:36706583
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