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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10669
Species: Mus musculus
RGD Object: Gene
Symbol: Gnas
Name: GNAS complex locus
Acc ID: CHEBI:8499
Term: propranolol
Definition: A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Chemical ID: MESH:D011433
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gnasincreases expressionISOGnas (Rattus norvegicus)6480464CTDPropranolol results in increased expression of GNAS mRNAPMID:20668454
Gnasmultiple interactionsISOGNAS (Homo sapiens)6480464CTD[Propranolol co-treated with ADRB2 protein] results in increased expression of GNAS proteinPMID:10455254
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