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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1553791
Species: Mus musculus
RGD Object: Gene
Symbol: Ugt2b1
Name: UDP glucuronosyltransferase 2 family, polypeptide B1
Acc ID: CHEBI:8489
Term: propiconazole
Definition: The cyclic ketal obtained by formal condensation of 1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone with pentane-1,2-diol. A triazole fungicide, it is used commercially as a diastereoisomeric mixture on soft fruit (including apricots, peaches, nectarines, plums and prunes), nuts (including peanuts, pecans and almonds), mushrooms, and grasses grown for seeds.
Chemical ID: MESH:C045950
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ugt2b1increases expressionEXP 6480464CTDpropiconazole results in increased expression of UGT2B1 mRNAPMID:21278054
Ugt2b1increases expressionISOUgt2b1 (Rattus norvegicus)6480464CTDpropiconazole results in increased expression of UGT2B1 mRNA; propiconazole results in increased expression of UGT2B17 mRNAPMID:16643972 PMID:17178689 PMID:19409404 PMID:19423681
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