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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318073
Species: Mus musculus
RGD Object: Gene
Symbol: Ikbke
Name: inhibitor of kappaB kinase epsilon
Acc ID: CHEBI:84491
Term: poly(I:C)
Definition: A mismatched double-stranded RNA with one strand being a polymer of inosinic acid, the other a polymer of cytidylic acid.
Chemical ID: MESH:D011070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ikbkeincreases phosphorylationEXP 6480464CTDPoly I-C results in increased phosphorylation of IKBKE proteinPMID:25780039
Ikbkemultiple interactionsEXP 6480464CTDAPPL1 protein promotes the reaction [Poly I-C results in increased phosphorylation of IKBKE protein]PMID:25780039
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