GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ar | affects binding | EXP | | 6480464 | CTD | prochloraz binds to AR protein | PMID:19833195 | Ar | multiple interactions | EXP | | 6480464 | CTD | prochloraz binds to and results in decreased activity of AR protein; prochloraz inhibits the reaction [Metribolone binds to AR protein]; prochloraz inhibits the reaction [Metribolone results in increased expression of AR mRNA] | PMID:14687758 PMID:15519604 PMID:15673607 PMID:18315717 | Ar | decreases activity | ISO | AR (Homo sapiens) | 6480464 | CTD | prochloraz results in decreased activity of AR protein | PMID:20821581 PMID:21251949 | Ar | multiple interactions | ISO | AR (Homo sapiens) | 6480464 | CTD | [procymidone co-treated with prochloraz co-treated with vinclozolin] inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; [propiconazole co-treated with prochloraz co-treated with tebuconazole] inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; [propiconazole co-treated with prochloraz] inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; [tebuconazole co-treated with prochloraz] inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; Dihydrotestosterone inhibits the reaction [prochloraz results in increased activity of AR protein]; prochloraz binds to and results in decreased activity of AR protein; prochloraz inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; prochloraz inhibits the reaction [Dihydrotestosterone affects the localization of and results in increased phosphorylation of AR protein]; prochloraz inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; prochloraz inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; prochloraz inhibits the reaction [Metribolone results in increased activity of AR protein] | PMID:15064155 PMID:18324785 PMID:20438827 PMID:21310686 PMID:25324206 PMID:26602169 PMID:33049310 | |
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