GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | GPX1 | increases activity | ISO | Gpx1 (Mus musculus) | 6480464 | CTD | Probucol results in increased activity of GPX1 protein | PMID:19770487 | GPX1 | multiple interactions | ISO | Gpx1 (Mus musculus) | 6480464 | CTD | Probucol inhibits the reaction [methylmercuric chloride results in decreased activity of GPX1 protein]; Probucol promotes the reaction [methylmercury II results in decreased expression of GPX1 mRNA] | PMID:19770487 PMID:27241350 | GPX1 | multiple interactions | ISO | Gpx1 (Rattus norvegicus) | 6480464 | CTD | Probucol inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of GPX1 mRNA]; Probucol inhibits the reaction [Doxorubicin results in decreased expression of GPX1 protein] | PMID:28734741 PMID:7805190 | |
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