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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68476
Species: Mus musculus
RGD Object: Gene
Symbol: Fads2
Name: fatty acid desaturase 2
Acc ID: CHEBI:83807
Term: paliperidone palmitate
Definition: A racemate comprising equimolar amounts of (R)- and (S)-paliperidone palmitate. A long-acting injectable formulation of paliperidone (the major active metabolite of risperidone) that is used for treatment of schizophrenia.
Chemical ID: MESH:D000068882
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fads2increases expressionISOFads2 (Rattus norvegicus)6480464CTDPaliperidone Palmitate results in increased expression of FADS2 mRNAPMID:21458237
Fads2multiple interactionsISOFads2 (Rattus norvegicus)6480464CTD[Paliperidone Palmitate results in increased expression of FADS2 mRNA] which results in increased abundance of Fatty Acids, UnsaturatedPMID:21458237
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