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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737571
Species: Homo sapiens
RGD Object: Gene
Symbol: HMGCS2
Name: 3-hydroxy-3-methylglutaryl-CoA synthase 2
Acc ID: CHEBI:83537
Term: 1-benzylpiperazine
Definition: A tertiary amino compound that is piperazine substituted by a benzyl group at position 1. It is a serotonergic agonist used as a recreational drug.
Chemical ID: MESH:C006737
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HMGCS2decreases expressionISOHmgcs2 (Rattus norvegicus)6480464CTDN-benzylpiperazine results in decreased expression of HMGCS2 mRNAPMID:26821219
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