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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69309
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fabp4
Name: fatty acid binding protein 4
Acc ID: CHEBI:83490
Term: 3,5,6-trichloropyridine-2-one
Definition: A pyridone that is pyridin-2(1H)-one substituted by chloro groups at positions 3, 5 and 6. It is a metabolite of the agrochemical chlorpyrifos.
Chemical ID: MESH:C012587
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fabp4multiple interactionsISORGD:7334546480464CTD3 5 6-trichloro-2-pyridinol promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA] 3 5 6-trichloro-2-pyridinol promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 protein]

PMID:32017950
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