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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3162
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nes
Name: nestin
Acc ID: CHEBI:83490
Term: 3,5,6-trichloropyridine-2-one
Definition: A pyridone that is pyridin-2(1H)-one substituted by chloro groups at positions 3, 5 and 6. It is a metabolite of the agrochemical chlorpyrifos.
Chemical ID: MESH:C012587
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nesaffects expressionISORGD:109716480464CTD3,5,6-trichloro-2-pyridinol affects the expression of NES mRNAPMID:25137620
Nesdecreases expressionISORGD:109716480464CTD3,5,6-trichloro-2-pyridinol results in decreased expression of NES mRNAPMID:23220036
Nesincreases expressionISORGD:109716480464CTD3,5,6-trichloro-2-pyridinol results in increased expression of NES mRNAPMID:23220036
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