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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69056
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Jak1
Name: Janus kinase 1
Acc ID: CHEBI:83267
Term: filipin III
Definition: A macrolide that is the major component of a mixture of four isomeric polyene macrolides isolated from Streptomyces filipinensis.
Chemical ID: MESH:D005372
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Jak1multiple interactionsISORGD:691026480464CTDFilipin inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased phosphorylation of JAK1 protein]PMID:19632255
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