Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736447
Species: Homo sapiens
RGD Object: Gene
Symbol: HSPA5
Name: heat shock protein family A (Hsp70) member 5
Acc ID: CHEBI:82818
Term: Z-Val-Phe-H
Definition: A dipeptide resulting from the formal condensation of the carboxy group of N-benzyloxycarbonyl-L-valine with the amino group of L-phenylalanine aldehyde. It is a potent cell-permeable inhibitor of calpain I and II, and is also a gamma-secretase inhibitor.
Chemical ID: MESH:C058076
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSPA5multiple interactionsISORGD:107426480464CTDcalpain inhibitor III inhibits the reaction [deoxynivalenol results in increased degradation of HSPA5 protein]

PMID:19336499
Go Back to source page   Continue to Ontology report