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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1595855
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Uhrf1
Name: ubiquitin-like with PHD and ring finger domains 1
Acc ID: CHEBI:8273
Term: plumbagin
Definition: A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 2 and 5 are substituted by methyl and hydroxy groups, respectively.
Chemical ID: MESH:C014758
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Uhrf1decreases expressionISOUHRF1 (Homo sapiens)6480464CTDplumbagin results in decreased expression of UHRF1 mRNA; plumbagin results in decreased expression of UHRF1 proteinPMID:36336213
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