GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk1 | increases phosphorylation | EXP | | 6480464 | CTD | Iron results in increased phosphorylation of MAPK1 protein | PMID:17172471 | Mapk1 | multiple interactions | EXP | | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Iron results in increased phosphorylation of MAPK1 protein]; [teferrol results in increased abundance of Iron] which results in increased phosphorylation of MAPK1 protein; [Vanadium co-treated with Iron] results in increased phosphorylation of MAPK1 protein; Deferiprone inhibits the reaction [Iron results in increased phosphorylation of MAPK1 protein]; Filipin inhibits the reaction [Iron results in increased phosphorylation of MAPK1 protein]; HRAS protein affects the reaction [Iron results in increased phosphorylation of MAPK1 protein]; Iron promotes the reaction [Asbestos, Amosite results in increased phosphorylation of MAPK1 protein]; PIK3R1 protein affects the reaction [Iron results in increased phosphorylation of MAPK1 protein]; SB 203580 promotes the reaction [Iron results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Iron results in increased phosphorylation of MAPK1 protein] | PMID:11306436 PMID:16728372 PMID:17172471 PMID:35307918 | Mapk1 | multiple interactions | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | [Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of MAPK1 protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of MAPK1 protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of MAPK1 protein]; Iron promotes the reaction [Arsenic results in increased phosphorylation of and results in increased activity of MAPK1 protein] | PMID:23100159 PMID:33285147 | Mapk1 | multiple interactions | ISO | Mapk1 (Mus musculus) | 6480464 | CTD | [ferrous chloride results in increased abundance of Iron] which results in increased phosphorylation of MAPK1 protein | PMID:30914277 | | ||||||||||||||||||||||
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