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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2503
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nqo1
Name: NAD(P)H quinone dehydrogenase 1
Acc ID: CHEBI:82664
Term: iron(0)
Definition: An elemental iron in which the atom has an oxidation state of zero.
Chemical ID: MESH:D007501
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nqo1increases expressionEXP 6480464CTDIron results in increased expression of NQO1 proteinPMID:35247364
Nqo1multiple interactionsEXP 6480464CTDleonurine promotes the reaction [Iron results in increased expression of NQO1 protein]PMID:35247364
Nqo1increases reductionISONQO1 (Homo sapiens)6480464CTDNQO1 protein results in increased reduction of IronPMID:17178108
Nqo1multiple interactionsISONQO1 (Homo sapiens)6480464CTD[Particulate Matter results in increased abundance of Iron] which results in increased expression of NQO1 mRNAPMID:26419736
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