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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344623
Species: Homo sapiens
RGD Object: Gene
Symbol: GSTA5
Name: glutathione S-transferase alpha 5
Acc ID: CHEBI:82664
Term: iron(0)
Definition: An elemental iron in which the atom has an oxidation state of zero.
Chemical ID: MESH:D007501
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GSTA5decreases expressionISOGsta1 (Mus musculus)6480464CTDIron results in decreased expression of GSTA1 proteinPMID:11755321
GSTA5increases expressionISOGsta1 (Mus musculus)6480464CTDIron results in increased expression of GSTA1 mRNA; Iron results in increased expression of GSTA1 proteinPMID:11755321
GSTA5multiple interactionsISOGsta5 (Rattus norvegicus)6480464CTD[Copper co-treated with Diethylnitrosamine co-treated with Iron] results in increased expression of GSTA5 mRNAPMID:20302851
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