GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fech | multiple interactions | ISO | FECH (Homo sapiens) | 6480464 | CTD | [pyridoxal isonicotinoyl hydrazone results in decreased abundance of Iron] which results in decreased expression of FECH protein | PMID:30517741 | Fech | multiple interactions | ISO | Fech (Mus musculus) | 6480464 | CTD | [Aminolevulinic Acid results in decreased activity of FECH protein] which results in increased abundance of Iron; [Griseofulvin results in decreased activity of FECH protein] which results in decreased uptake of Iron; [Porphobilinogen results in decreased activity of FECH protein] which results in increased abundance of Iron; heme arginate inhibits the reaction [[Griseofulvin results in decreased activity of FECH protein] which results in decreased uptake of Iron] | PMID:15078340 | |
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