GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | multiple interactions | EXP | | 6480464 | CTD | [Particulate Matter results in increased abundance of Iron] which results in increased secretion of IL1B protein | PMID:32007923 | Il1b | increases expression | ISO | Il1b (Rattus norvegicus) | 6480464 | CTD | Iron results in increased expression of IL1B protein | PMID:35247364 | Il1b | multiple interactions | ISO | Il1b (Rattus norvegicus) | 6480464 | CTD | [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of IL1B protein; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of IL1B mRNA; [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of IL1B protein; leonurine inhibits the reaction [Iron results in increased expression of IL1B protein]; lipopolysaccharide A promotes the reaction [Iron results in increased secretion of IL1B protein]; taxifolin inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of IL1B protein] | PMID:16958088 PMID:22198552 PMID:32828744 PMID:35247364 | | ||||||||||||||||||||||
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