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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akt1
Name: AKT serine/threonine kinase 1
Acc ID: CHEBI:82619
Term: icariside II
Definition: A glycosyloxyflavone that is 3,5,7-trihydroxy-4'-methoxy-8-prenylflavone in which the hydroxy group at position 3 has been converted into its alpha-L-rhamnopyranoside.
Chemical ID: MESH:C060988
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akt1decreases phosphorylationISORGD:7329096480464CTDbaohuoside I results in decreased phosphorylation of AKT1 protein

PMID:25119583
Akt1multiple interactionsISORGD:7329096480464CTDbaohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]

PMID:25119583
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