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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10118
Species: Mus musculus
RGD Object: Gene
Symbol: Agt
Name: angiotensinogen
Acc ID: CHEBI:82615
Term: diminazene diaceturate
Definition: An N-acetylglycinate salt resulting from the reaction of diminazene with 2 mol eq. of N-acetylglycine.
Chemical ID: MESH:C003915
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agtincreases expressionEXP 6480464CTDdiminazene aceturate results in increased expression of AGT protein modified formPMID:25301841
Agtincreases expressionISOAGT (Homo sapiens)6480464CTDdiminazene aceturate results in increased expression of AGT protein alternative formPMID:26862037
Agtmultiple interactionsISOAGT (Homo sapiens)6480464CTD7-Ala-angiotensin (1-7) inhibits the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of AGT protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [diminazene aceturate promotes the reaction [Lipopolysaccharides results in increased expression of AGT protein alternative form]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of AGT protein]]; ACE2 protein affects the reaction [diminazene aceturate promotes the reaction [Lipopolysaccharides results in increased expression of AGT protein alternative form]]; diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of AGT protein]; diminazene aceturate promotes the reaction [Lipopolysaccharides results in increased expression of AGT protein alternative form]PMID:26862037
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