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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1553797
Species: Mus musculus
RGD Object: Gene
Symbol: Kif11
Name: kinesin family member 11
Acc ID: CHEBI:8249
Term: piroxicam
Definition: A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxide with the exocyclic nitrogen of 2-aminopyridine. A non-steroidal anti-inflammatory drug of the oxicam class, it is used to relieve pain and works by preventing the production of endogenous prostaglandins involved in the mediation of pain, stiffness, tenderness and swelling.
Chemical ID: MESH:D010894
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kif11decreases expressionISOKIF11 (Homo sapiens)6480464CTDPiroxicam results in decreased expression of KIF11 mRNAPMID:21858171
Kif11multiple interactionsISOKIF11 (Homo sapiens)6480464CTDCisplatin affects the reaction [Piroxicam results in decreased expression of KIF11 mRNA]PMID:21858171
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