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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3001
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lepr
Name: leptin receptor
Acc ID: CHEBI:8248
Term: pirimicarb
Definition: An aminopyrimidine that is N,N,4,5-tetramethylpyrimidin-2-amine substituted by a (dimethylcarbamoyl)oxy group at position 4.
Chemical ID: MESH:C011994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Leprmultiple interactionsEXP 6480464CTD[2-amino-3-chloro-1, 4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of LEPR mRNA

PMID:29321614
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