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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736306
Species: Homo sapiens
RGD Object: Gene
Symbol: IL4
Name: interleukin 4
Acc ID: CHEBI:82436
Term: decabromodiphenyl ether
Definition: A polybromodiphenyl ether that is diphenyl ether in which all of the hydrogens have been replaced by bromines.
Chemical ID: MESH:C010902
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL4increases expressionISOIl4 (Mus musculus)6480464CTDdecabromobiphenyl ether results in increased expression of IL4 mRNA; decabromobiphenyl ether results in increased expression of IL4 proteinPMID:22972382 PMID:33571618
IL4increases secretionISOIl4 (Mus musculus)6480464CTDdecabromobiphenyl ether results in increased secretion of IL4 proteinPMID:33571618
IL4multiple interactionsISOIl4 (Mus musculus)6480464CTDdecabromobiphenyl ether promotes the reaction [[lead chloride results in increased abundance of Lead] which results in increased expression of IL4 protein]PMID:30836164
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