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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620436
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cga
Name: glycoprotein hormones, alpha polypeptide
Acc ID: CHEBI:82436
Term: decabromodiphenyl ether
Definition: A polybromodiphenyl ether that is diphenyl ether in which all of the hydrogens have been replaced by bromines.
Chemical ID: MESH:C010902
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDdecabromobiphenyl ether results in increased expression of CGA mRNA

PMID:23640034
multiple interactionsISORGD:13485906480464CTDdecabromobiphenyl ether inhibits the reaction [CGA protein results in increased secretion of Progesterone]

PMID:31132478
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.