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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2261
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Camk2a
Name: calcium/calmodulin-dependent protein kinase II alpha
Acc ID: CHEBI:82436
Term: decabromodiphenyl ether
Definition: A polybromodiphenyl ether that is diphenyl ether in which all of the hydrogens have been replaced by bromines.
Chemical ID: MESH:C010902
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Camk2adecreases expressionEXP 6480464CTDdecabromobiphenyl ether results in decreased expression of CAMK2A protein; decabromobiphenyl ether results in decreased expression of CAMK2A protein modified formPMID:30404998
Camk2aincreases expressionEXP 6480464CTDdecabromobiphenyl ether results in increased expression of CAMK2A mRNAPMID:23640034
Camk2aincreases expressionISOCamk2a (Mus musculus)6480464CTDdecabromobiphenyl ether metabolite results in increased expression of CAMK2A protein; decabromobiphenyl ether results in increased expression of CAMK2A proteinPMID:19380496 PMID:25194327
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