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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:82436
Term: decabromodiphenyl ether
Definition: A polybromodiphenyl ether that is diphenyl ether in which all of the hydrogens have been replaced by bromines.
Chemical ID: MESH:C010902
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxincreases expressionISOBax (Mus musculus)6480464CTDdecabromobiphenyl ether results in increased expression of BAX mRNA; decabromobiphenyl ether results in increased expression of BAX proteinPMID:28572024 PMID:31039416 PMID:35950316
Baxincreases expressionISOBAX (Homo sapiens)6480464CTDdecabromobiphenyl ether results in increased expression of BAX mRNAPMID:26206603
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