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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1345118
Species: Homo sapiens
RGD Object: Gene
Symbol: PARP1
Name: poly(ADP-ribose) polymerase 1
Acc ID: CHEBI:82405
Term: Benzoyl peroxide
Definition: A carbonyl compound that has formula C14H10O4.
Chemical ID: MESH:D001585
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PARP1increases activityEXP 6480464CTDBenzoyl Peroxide results in increased activity of PARP1 proteinPMID:2120135 PMID:2126186
PARP1multiple interactionsEXP 6480464CTD3-aminobenzamide inhibits the reaction [Benzoyl Peroxide results in increased activity of PARP1 protein]; Butylated Hydroxytoluene inhibits the reaction [Benzoyl Peroxide results in increased activity of PARP1 protein]; CAT protein inhibits the reaction [Benzoyl Peroxide results in increased activity of PARP1 protein]PMID:2120135 PMID:2126186
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